Protein controlling magnesium identified as therapeutic target for non-alcoholic fatty liver disease

An international team of researchers has identified the CNNM4 protein as a key regulator of magnesium in the liver and potential therapeutic target for non-alcoholic fatty liver disease, according to a study published in the Journal of Hepatology. Non-alcoholic steatohepatitis, a form of fatty liver disease characterized by inflammation and liver fibrosis, is associated with […]

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Artificial intelligence reveals current drugs that may help combat Alzheimer’s disease

New treatments for Alzheimer’s disease are desperately needed, but numerous clinical trials of investigational drugs have failed to generate promising options. Now a team at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) has developed an artificial intelligence-based method to screen currently available medications as possible treatments for Alzheimer’s disease. The method could represent […]

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Failing to see the forest for the trees may prevent better cardiovascular outcomes

Managing single risk factors like blood pressure rather than looking at overall risk may be wasting scarce resources in countries where cardiovascular disease (CVD) is on the rise, according to a new study. Researchers looked at country-specific levels of cardiovascular risk, associations with socio-demographic factors and whether WHO guidelines on the use of blood pressure […]

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